Exosomes and polynucleotides (PDRN) are both regenerative treatments gaining rapid popularity in UK aesthetics. But they work differently, suit different patients, and deliver different outcomes. This comparison helps you decide which — or both — to add to your treatment menu.
How They Work
Exosomes are nanoscale vesicles that deliver multiple signalling molecules to target cells, triggering comprehensive regeneration. Polynucleotides are DNA fragments that activate A2A purinergic receptors, stimulating fibroblast activity and collagen production. Both are biostimulatory but through different mechanisms.
Treatment Comparison
Exosomes excel at: comprehensive rejuvenation, scar treatment, hair restoration, post-procedure recovery. Polynucleotides excel at: skin hydration, under-eye treatment, biostimulation, skin quality improvement. Both address: fine lines, skin laxity, and overall skin health.
Pricing and Margins
Exosome treatments typically command higher per-session pricing (GBP 300-600) due to novelty and efficacy. Polynucleotide treatments are priced similarly to skin boosters (GBP 200-400). Both offer strong margins for practitioners using wholesale product pricing.
Our Recommendation
Offer both. They serve different patient needs and can be combined for synergistic results. Start with whichever aligns best with your existing treatment menu and patient demographics.