Tranexamic Acid

Tranexamic acid is the rising star of hyperpigmentation treatment. Originally used to reduce bleeding in surgery, it has been discovered to be remarkably effective at inhibiting melanin production — making it a powerful treatment for melasma, dark spots, and post-inflammatory hyperpigmentation.

What Is Tranexamic Acid?

Tranexamic acid works by inhibiting plasminogen activator, which reduces the interaction between keratinocytes and melanocytes. This disrupts the melanin production pathway without the irritation associated with hydroquinone or high-concentration vitamin C.

Clinical Evidence

Clinical studies show tranexamic acid reduces melasma severity scores by up to 49% in 12 weeks. It is effective in all skin types (Fitzpatrick I-VI) and does not cause rebound hyperpigmentation when discontinued.

For Aesthetic Professionals

Tranexamic acid is becoming essential in pigmentation protocols. It's safe for all skin types, can be combined with retinol and vitamin C, and is particularly effective for resistant melasma cases.